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M9490001.TXT
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1994-09-03
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Document 0001
DOCN M9490001
TI Acute severe rhabdomyolysis in an human immunodeficiency
virus-seropositive patient associated with rising anti-coxsackie B viral
titers.
DT 9411
AU Beressi A; Sunheimer RL; Huish S; Finck C; Pincus MR; Department of
Pathology, SUNY Health Science Center, Syracuse; 13210.
SO Ann Clin Lab Sci. 1994 May-Jun;24(3):278-81. Unique Identifier :
AIDSLINE MED/94324800
AB Very recently there have been sporadic reports of polymyositis in
patients who are positive for human immunodeficiency virus (HIV). The
cause of this condition has not been documented. Recent evidence has
been presented which indicates that the Coxsackie B virus may be a
causative factor. Presentation is made of a patient, a drug abuser who
was found to be HIV-positive with severe polymyositis manifested by
generalized muscle weakness and a total serum creatinine kinase that
reached the unusually high level of > 600,000 U/L. This patient was
found to have a rise in titer of Coxsackie B-4 virus antibodies. He was
negative for a variety of possible infectious causes of this condition
and was negative for both antinuclear antibodies (ANA) and rheumatoid
factor (RF). It is concluded that a polymyositis may indeed be
associated with immunosuppressed states and that Coxsackie B-4 virus may
be an important causative factor.
DE Adult Antibodies, Viral/*BLOOD Case Report Coxsackievirus
Infections/*COMPLICATIONS Coxsackieviruses B/*IMMUNOLOGY Human HIV
Seropositivity/*COMPLICATIONS Male Rhabdomyolysis/*COMPLICATIONS
Substance Abuse JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).